Pathogen traits, such as the virulence of an infection, can vary significantly between patients. A major challenge is to measure the extent to which genetic differences between infecting strains explain the observed variation of the trait. This is quantified by the trait’s broad-sense heritability, \(H^2\). The patherit R-package allows to compare various estimators of pathogen trait heritability in data simulated using the toyepidemic R-package, and in real epidemiological data.
The following methods are available:
You can install the most recent version of the package from github:
For using the package, read the package Get started guide.
The package source-code is available on github.
Check-out the package web-page for the latest news and further documentation.